Wegovy is a GLP-1 receptor agonists and a Brand name for the drug known as Semaglutide. It helps with weight loss by mirroring the function of GLP-1 (glucagon-like-peptide-1), a hormone that is naturally occurring in the body. In a brief summary GLP-1 agonists promote the release of insulin to help regulate blood sugar after meals, slows gastric emptying, and reduces appetite.

Zepbound is a Glucose Dependent Insulinotropic Polypeptide (GIP) AND a Glucagon-Like Peptide (GLP-1) Receptor agonist. It is the brand name for the drug known as Tirzepatide. Instead of working on only one naturally occurring hormone in the body, like Wegovy (GLP-1), it works on two (GLP-1 and GIP) hormones in the body to help promote weight loss and improve blood sugar. In summary Zepbound not only promotes the release of insulin like wegovy but also reduces glucagon levels to help regulate blood sugar before and after meals, slows gastric emptying, and reduces appetite.
 

• Insulin is a natural occurring hormone that reduces blood sugar levels.
• Glucagon is a natural occurring hormone that increases blood sugar.

The main differences and similarities between the two drugs include:

• Hormones influenced
  • Zepbound increases insulin and decreases glucagon.
  • Wegovy increases insulin.
• Dosing strengths
  • Zepbound is available up to 15mg and Wegovy is available up to 2.4mg.
• FDA approval
  • Zepbound is FDA approved for treatment of overweight and obesity diagnosis..
  • Wegovy is FDA approved for the treatment of overweight and obesity diagnosis.
• Average weight loss
  • Some adults taking Zepbound achieved up to 25% weight loss at max dosing.
  • 1 in 3 adults taking Wegovy achieved 20% weight loss.

Both drugs are to be used in conjunction with diet and exercise to achieve desired results. Please contact our office to find out how we can help you to get started on your weight loss journey.